변종혁 사진
변종혁
영문이름
Byun, Jong Hyuk
직위(직급)
조교수
전화번호
051-510-3311
팩스번호
051-581-1458
이메일
maticax@pusan.ac.kr
사이트
연구분야
시스템생물학, 약동학/약력학(PKPD), 종양과 면역모델, 확률과정 및 확률미분방정식, 파라미터 추정, 베이지안 추론, 과학 시스템 시뮬레이션
연구실
607-518

학력 (Education)

 2016.3-2019.2 부산대학교 수학과 대학원 박사졸업 (시스템생물학 및 PKPD)

 2006.8-2011.6 신시네티대학교 수료 (응용수학, biofilm modeling in pipe)

 2003.3-2005.2 부산대학교 수학과 대학원 석사졸업 (PDE, Energy decay)

 1997.3-2002.8 부산대학교 수학과 학부 졸업

 

경력 (Experience)

 2019.3~2022.8 부산대 수리과학연구소 연수연구원 및 연구교수

 2012.6~2016.2  한국과학영재학교 (KSA) 강의

 

대표논문 (Selected Publications)

 1. Jong Hyuk Byun, Il Hyo Jung, Mathematical modeling of antibody drug conjugates with the target and tubulin dynamics to predict AUC, Journal of Theoretical Biology, 443, 2018, 113-124

 2. Byun, Jong Hyuk, Jung, Il Hyo, Modeling to capture bystander-killing effect by released payload in target positive tumor cells, BMC Cancer, 19, 2019, 194

 3. S Kim, JH Byun, IH Jung, Global stability of an SEIR epidemic model where empirical distribution of incubation period is approximated by Coxian distribution, Advances in Difference Equations, 469, 2019, 113-124 

 4. Jong Hyuk Byun, Il Hyo Jung, East Asian Mathematical Journal, A fractional-order tumor growth inhibition model to capture tumor reduction, 36, 2020, 81-90

 5. Sungchan Kim, Jong Hyuk Byun, Anna Park, and Il Hyo Jung, A mathematical model for assessing the effectiveness of controlling relapse in Plasmodium vivax malaria endemic in the Republic of Korea, PlosOne, 15 (1), 2020, e0227919

 6. Jong Hyuk Byun, Dong-Gyun Han, Hyun-Jong Cho, In-Soo Yoon, Il Hyo Jung, Recent advances in physiologically based pharmacokinetic and pharmacodynamic models for anticancer nanomedicines, Archives of Pharmacal Research, 43, 2020, 80-99

 7. JH Byun, IH Jung, Mathematical modeling of the receptor-mediated endocytosis process of targeted therapeutic agents in drug delivery systems, Applied Mathematical Modelling, 79, 2020, 300-313

 8. Sungchan Kim, Yong Dam Jeong, Jong Hyuk Byun, Giphil Cho, Anna Park, Jae Hun Jung, Yunil Roh, Sooyoun Choi, Ibrahim Malik Muhammada, Il Hyo Jung, Evaluation of COVID-19 epidemic outbreak caused by temporal contact-increase in South Korea, International Journal of Infectious Diseases, 2020

 9. Jong Hyuk Byun, Anna Park, Il Hyo Jung, Receptor-Mediated Endocytosis Modeling of Antibody-Drug Conjugates to the Released Payload within the Intracellular Space Considering Target Antigen Expression Levels, Journal of Applied Analysis and Computation, 2020

 10. Anna Park, Sangil Kim, Il Hyo Jung, Jong Hyuk Byun, An immune therapy model for effective on inflammatory bowel disease, PlosOne, 2020

 11.  Jong Hyuk Byun, Il Hyo Jung, A phase-specific cancer immune model considering acquired resistance to therapeutic agents, Applied Mathematics and Computation, 2021

 12. Seong-Wook Seo, Dong-Gyun Han, Eugene Choi, Taeuk Park, Jong Hyuk Byun, Hyun-Jong Cho, Il Hyo Jung, In-Soo Yoon, Development and application of a physiologically based pharmacokinetic model for entrectinib in rats and scale-up to humans: Route-dependent gutwall metabolism, Biomedicine & Pharmacotherapy, 2022

 13. Jong Hyuk Byun and Il Hyo Jung, Stochastic target-mediated drug disposition model based on birth-death process and its parameter inference using approximate Bayesian computation-MCMC, Applied Mathematical Modelling, 2022

 14.  Jong Hyuk Byun, In?SooYoon, SongYi Lee, Hyun?Jong Cho & Il Hyo Jung, Extended transit compartment model to describe tumor delay using Coxian distribution, Scientific reports, 2022

 15. 정일효,윤인수,변종혁,Kim, Kwang Su, Fractional transit compartment model for describing drug delayed response to tumors using Mittag-Leffler distribution on age- structured PKPD model, PUBLIC LIBRARY SCIENCE, 2022

 16. 변종혁,김광수, A Hybrid GCN and Filter-Based Framework for Channel and Feature Selection: An fNIRS-BCI Study, JOHN WILEY & SONS INC, 2023.03.

 17. 변종혁, 김광수, Analytical Solutions for Unsteady Thin Film Flow with Internal Heating and Radiation, Hindawi Publishing Corporation, 2023.05.

 18. 윤인수,윤화영,변종혁,한동균,곽진숙, Physicochemical characterization and phase II metabolic profiling of echinochrome A, a bioactive constituent from sea urchin, and its physiologically based pharmacokinetic modeling in rats and humans, EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2023.06.

19. 변종혁,김광수,Muhammad Umair Ali,Muhammad Bilal,Muhammad Safdar,Shoaib Ahmed,Karam Dad Kallu,Muhammad Umair Ali, Numerical approximations for fluid flow and heat transfer in the boundary layer with radiation through multiple Lie similarity transformations, FRONTIERS MEDIA SA, 2023.07.

20.  변종혁,김광수, Artificial Neural Network Models: Implementation of Functional Near-Infrared Spectroscopy-based Spontaneous Lie Detection in an Interactive Scenario, FRONTIERS RES FOUND, 2023.12.

21. 변종혁,김재경,윤휘열, Validity conditions of approximations for a target-mediated drug disposition model: A novel first-order approximation and its comparison to other approximations, PUBLIC LIBRARY SCIENCE, 2024.04.

22. 변종혁,YONG DAM JEONG, Mathematical modelling to assess the impact of stress on temperature-dependent sex determination in teleost fish, 한국전산응용수학회및전산수학연구회, 2024.04. 


● 대학원생(Graduate student)


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